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Pfizer wins new FDA approval for Tukysa in breast cancer

Pfizer is strengthening its position in HER2-positive breast cancer. The FDA has approved Tukysa as a first-line maintenance treatment after a phase III trial showed that the combination extended progression-free survival by 8.6 months.
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It is Pfizer’s second FDA approval in less than four months for first-line maintenance treatment in HER2-positive breast cancer.

This time, the approval covers Tukysa (tucatinib), a tyrosine kinase inhibitor that can now be used alongside Roche’s antibody drugs Herceptin and Perjeta in patients with advanced HER2-positive breast cancer that cannot be surgically removed or has spread to other organs.

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